Financed projects

 

Funding sources

 

Carbonomics: [FR] Développement des protocoles innovants pour l’exploration clinico-biologique de patients atteints de glioblastomes et l’amélioration du guidage thérapeutique [CEA, inter DRT/DRF coupling program, 2014-2015]

Main collaborators:

EDyP correspondent: V. Brun

 

 

ProteoRE: Design and implementation of a user-oriented web-based platform for MS-based proteomics data exploration. [IFB 2015, 2016-2018?]

Main collaborators:

EDyP correspondent: Y. Vandenbrouck

 

 

NASH: Evaluation of plasma biomarkers for differential steatosis versus non alcoholic hepatic steatosis diagnosis. [UGA Agir 2016]

Main collaborators: 

EDyP correspondent: V. Brun

 

 

INTACT : High performance mass spectrometry for top-down protein analysis. [FRM, Large Equipments 2012, 2013-2016]

Main collaborators:

EDyP correspondent: C. Masselon

 

 

FungiBet : Investigating a potential new antifungal drug target: Structure, function and inhibition of fungal BET bromodomains [ANR, Generic 2014, 2015-2017]

Main collaborators:

EDyP correspondent: J. Govin

 

Pandoravirus : Functional and molecular characterization of Pandoraviruses [ANR, Edition 2013, 2014-2018]

Main collaborators:

EDyP correspondent: Y. Couté

REGtheREG : Regulating the Regulators: post-translational modifications of plant RNA silencing factors [ANR, Generic 2014, 2014-2018]

Main collaborators:

EDyP correspondent: D. Pflieger

HistPTMs : Discovery and characterization of new histones post-translational modifications  [CEA scholarship Irtelis 2015, 2015-2018]

Main collaborators:

PhD : S. El Kennani; EDyP correspondent: D. Pflieger

 

 

WilProj : Translational proteomic analysis of the Wilson disease physiopathology [CEA scholarship Irtelis 2015, 2015-2018]

Main collaborators:

PhD : M. Lacombe; EDyP correspondent: V. Brun

 

 

RESET: Arrest and restart of the gene expression machinery in bacteria: from mathematical models to biotechnological applications [ANR, « Investissement d’Avenir » Bioinformatics-2011 edition, 2012-16]

Main collaborators:

  • H. De jong, INRIA, Grenoble [web]
  • J. Geiselmann, LAPM, La Tronche [web]
  • I. Mihalcescu, LIPHY, Grenoble [web]
  • O. Martin, Génétique Végétale du Moulon [web]
  • J-L. Gouze, INRIA Sophia-Antipolis – Méditerranée [web]
  • R. Figge, Metabolic Explorer SA [web]

EDyP correspondent: C. Bruley / M. Ferro

 

 

TOXOHDAC: The HDAC3 regulatory network defines a new epigenetic path to explore Toxoplasma gondii differentiation and pathogenesis [ANR, blank program 2012 edition, 48 months]

Main collaborators:

  • M-A. Hakimi, CNRS, UMR5163-LAPM, Grenoble (coordinator)
  • H. Belrhali, EMBL Grenoble

EDyP correspondent: Y. Couté

 

 

RNAGermSilence: RNA, heterochromatin and germ cell differentiation: RNA-driven epigenetic gene silencing [ANR, blank program 2013 edition, 48 months]

Main collaborators:

  • A. Verdel, INSERM/UJF U23, Grenoble (coordinator)
  • R. Pillai, EMBL Grenoble

 

EDyP correspondent: Y. Couté

 

 

PRIME-XS: Proteomics Research Infrastructure Maximising knowledge EXchange and access (XS) [7th Framework Programme of the European Union, Contract no. 262067, 2011-15]

All partners in this Infrastructure Project

  • Utrecht University (coordinator), The Netherlands
  • Flemish Institute for Biotechnology, Belgium
  • University of Zürich, Switzerland
  • ETH Zürich, Switzerland
  • University of Copenhagen, Denmark
  • CRG Barcelona, Spain
  • University of Cambridge, United Kingdom
  • IMP, Vienna, Austria
  • CEA, Grenoble, France (EDyP)
  • Eberhard Karls Universität Tübingen, Germany
  • EMBL Outstation, EBI, United Kingdom
  • Max Planck Gesellschaft, Germany

EDyP correspondent: J. Garin* / C. Bruley

website at : http://www.primexs.eu/

*head of the IRTSV institute (CEA/DSV/IRTSV)

 

 

ProFi: Proteomics French Infrastructure [ANR, Infrastructures Nationales de Biologie et Santé, 2012-19]

All partners in this Infrastructure Project

  • B. Monsarrat, O. Schiltz, IPBS/PMSB, Toulouse [web]
  • A. Van Dorsselaer, C. Carapito, Institut Hubert Curien/ LSMBO, Strasbourg [web]
  • M. Ferro, DSV/IRTSV/BGE/EDyP, Grenoble

EDyP correspondent: J. Garin* / M. Ferro

website at : http://www.profiproteomique.fr/

*head of the IRTSV institute (CEA/DSV/IRTSV)

COPDETOX: Copper chelators targeted at the liver: an innovative treatment of hepatic copper overload [ANR, emergence 2011; CEA, Technologies for Health;  2012-14]

Main collaborators:

 

EDyP correspondent: M. Jaquinot

 

 

GRAL: Grenoble Alliance for Integrated Structural Cell Biology (Axis 2: The chloroplast compartment and its substructures) [ANR, call Labex, 2012-15]

http://www.agence-nationale-recherche.fr/investissementsdavenir/AAP-LABEX-2011.html

Main collaborators:

 

EDyP correspondent: M. Ferro

website at : http://www.labex-gral.fr/

 

 

DYNOTEP – DYNamics Of The Endocytic Proteome: a systemic perspective on trafficking and maturation [ANR, Progamme Blanc SVSE6 – 01/2013]

Main collaborators: 

  • Laurence Aubry [PI], CEA, DSV, iRTSV/BGE, Grenoble
  • Alahme Douzal, UJF, AMA/LIG Grenoble

EDyP correspondent: C. Masselon

 

NEMS-MS – Nanosystem-based Mass Spectrometry [ANR, ASTRID – 01/2013, IDEAS ERC 2013]

Main collaborators: 

  • Sébastien Hentz [PI], CEA, DRT, LETI, Grenoble
  • Richard Cole, UPMC, Paris VI 

EDyP correspondent: C. Masselon

 

 

DETOXMET: Evaluation d’un candidat médicament pour traiter les surcharges en métaux, Title in English, please [GRAVIT, 2012-12]

Main collaborators: 

EDyP correspondent: M. Jaquinot

 

 

NRBC: Multiplex quantification of enterotoxins and ricin in complex medium by mass spectrometry [interministerial/ CEA R&D program of fight against terrorism, 2012-13, 2015]

Main collaborators:

EDyP correspondent: V. Brun